NanoString Technologies

 
 
NanoString 1018

NanoString’s Digital Nucleic Acid Detection


NanoString technology uses unique color-coded molecular barcodes that can hybridize directly to many different types of target nucleic acid molecules, making it ideal for a range of discovery and translational research applications. Their portfolio of application-specific solutions currently includes kits for gene expression, copy number variation and miRNA analysis.
 
NanoString is committed to expanding the range of applications enabled on the nCounter Analysis System and are continually working with customers and other partners to develop novel solutions for current and emerging areas of biological research and discovery.

 
Introducing the nCounter® Host Response Panel
Profile immune response dynamics to SARS-CoV-2 & other pathogens (including webinars).
more >

 
Digital Spatial Profiling (DSP) Technology Gene Expression Analysis miRNA Expression Analysis
 
 
miRGE™ Analysis Copy Number Variation Analysis ChIP-String Expression Analysis
 

Digital Spatial Profiling (DSP) Technology
NanoString’s GeoMx™ Digital Spatial Profiler combines standard immunofluorescence techniques with digital optical barcoding technology to perform highly multiplexed, spatially resolved profiling experiments. In a single reaction, the DSP technology performs whole slide imaging with up to four fluorescent stains to capture tissue morphology and select regions of interest for high plex profiling. The ability to perform tissue morphology guided profiling experiments increases the likelihood of capturing rare events often missed by typical grind and bind assays. The DSP chemistry enables spatially resolved high plex profiling of RNA and protein targets on just two serial sample sections. The ability to perform multianalyte analysis enables deep characterization of the sample.
Gene Expression Analysis
Gene Expression CodeSets for the nCounter Analysis System offer a cost-effective way to analyze the expression levels of up to 800 genes simultaneously, with sensitivity comparable to qPCR. The system can directly assay tissue and blood lysates as well as FFPE extracts in a simple workflow that only requires 15 minutes of hands-on time per reaction
miRNA Expression Analysis
With multiplexed target profiling of miRNA transcriptomes in a single reaction, the nCounter miRNA Expression Assay Kits deliver high levels of sensitivity, specificity, precision, and linearity across a wide range of research areas such as oncology, neurobiology, developmental biology, and stem-cell research
miRGE™ Analysis
Revolutionizing the workflow for profiling miRNA and mRNAs expression, nCounter miRGE CodeSets allow for the simultaneous profiling of both miRNAs and mRNAs in a single reaction. Two assays in a single tube means fewer pipetting steps, less preparation time and only a single sample aliquot. miRGE CodeSets can profile samples from FFPE extracts, as well as from several other precious/difficult sample types.
Copy Number Variation Analysis
The nCounter Copy Number Variation CodeSets enable better results, faster, and with substantially less effort than PCR or arrays. With the lowest hands-on time of any platform, these CodeSets provide everything needed to interrogate copy number variants in a single multiplexed reaction.
ChIP-String Expression Analysis
The nCounter Custom ChIP-String Assay is a read-out method designed to measure dsDNA fragments that have been enriched via various user-defined chromatin immunoprecipitation protocols. Based on NanoString’s molecular barcoding technology the assay can reliably quantify as few as 5,000 molecules of DNA without the need for amplification.